Publication Type |
Journal Article |
Title |
Alkylammonium Guest Induced-Fit Recognition by a Flexible Dihomooxacalix[4]arene Derivative |
Authors |
Carmen Talotta Carmine Gaeta Margherita De Rosa José do Rosário Ascenso Paula M. Marcos Placido Neri |
Groups |
BioMol |
Journal |
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY |
Year |
2016 |
Month |
January |
Volume |
|
Number |
1 |
Pages |
158-167 |
Abstract |
The conformationally mobile tetramethoxy-dihomooxacalix[4]arene 1c is able to interact with linear and branched alkylammonium guests through an induced-fit process mainly driven by H-bonds and cation- interactions. Although free 1c adopts a 1,4-alternate conformation in solution, in the presence of linear nBuNH(3)(+) and branched sBuNH(3)(+) and iPrNH(3)(+) guests, it preferentially forms endo-complexes in a cone conformation through adaptive structural change in response to the presence of the ammonium guests. In accordance with previous results, the DFT-optimized structures of the complexes indicate that they are mainly stabilized by H-bonding interactions between the guest ammonium group and the host CH2OCH2 ethereal bridge. |
DOI |
http://dx.doi.org/10.1002/ejoc.201501319 |
ISBN |
|
Publisher |
WILEY-V C H VERLAG GMBH |
Book Title |
|
ISSN |
1434-193X |
EISSN |
1099-0690 |
Conference Name |
|
Bibtex ID |
ISI:000368022100025 |
Observations |
|