| Publication Type |
Journal Article |
| Title |
The sub-cellular fate of mercury in the liver of wild mullets (Liza aurata) - Contribution to the understanding of metal-induced cellular toxicity |
| Authors |
Olinda Araujo Patricia Pereira Rute Cesário Mario Pacheco Joana Raimundo |
| Groups |
|
| Journal |
MARINE POLLUTION BULLETIN |
| Year |
2015 |
| Month |
June |
| Volume |
95 |
| Number |
1 |
| Pages |
412-418 |
| Abstract |
Mercury is a recognized harmful pollutant in aquatic systems but still little is known about its subcellular partitioning in wild fish. Mercury concentrations in liver homogenate (whole organ load) and in six sub-cellular compartments were determined in wild Liza aurata from two areas - contaminated (LAR) and reference. Water and sediment contamination was also assessed. Fish from LAR displayed higher total mercury (tHg) organ load as well as in sub-cellular compartments than those from the reference area, reflecting environmental differences. However, spatial differences in percentage of tHg were only observed for mitochondria (Mit) and lysosomes plus microsomes (Lys + Mic). At LAR, Lys + Mic exhibited higher levels of tHg than the other fractions. Interestingly, tHg in Mit, granules (Gran) and heat-denaturable proteins was linearly correlated with the whole organ. Low tHg concentrations in heat stable proteins and Gran suggests that accumulated levels might be below the physiological threshold to activate those detoxification fractions. (C) 2015 Elsevier Ltd. All rights reserved. |
| DOI |
http://dx.doi.org/10.1016/j.marpolbul.2015.03.036 |
| ISBN |
|
| Publisher |
PERGAMON-ELSEVIER SCIENCE LTD |
| Book Title |
|
| ISSN |
0025-326X |
| EISSN |
1879-3363 |
| Conference Name |
|
| Bibtex ID |
ISI:000356741000060 |
| Observations |
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