Publication Type Journal Article
Title Short synthesis of the natural product 3 beta-hydroxy-labd-8(17)-en-15-oic acid via microbial transformation of labdanolic acid
Authors Luís M. T. Frija Helga Garcia Catia Rodrigues Isabel Martins Nuno R. Candeias Vânia André M. Teresa Duarte Cristina Silva Pereira Carlos A. M. Afonso
Groups BIOMOL
Journal PHYTOCHEMISTRY LETTERS
Year 2013
Month May
Volume 6
Number 2
Pages 165-169
Abstract Starting from labdanolic acid, extracted from Cistus ladaniferus plant, the first synthesis of the natural product 3b-hydroxy-labd-8(17)-en-15-oic acid was achieved, via microbial transformation mediated by Penicillium janczewskii followed by dehydration. The structure of a new labdane diterpene, namely 3 beta-hydroxy-labdanolic acid, was elucidated by X-ray crystallography and spectroscopic data. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.
DOI http://dx.doi.org/10.1016/j.phytol.2012.12.005
ISBN
Publisher
Book Title
ISSN 1874-3900
EISSN
Conference Name
Bibtex ID ISI:000318271400003
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