Publication Type Journal Article
Title Building 1,2,4-Thiadiazole: Ten Years of Progress
Authors Luís M. T. Frija Armando J.L. Pombeiro Maximilian N. Kopylovich
Groups CCC
Journal EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Year 2017
Month May
Volume
Number 19
Pages 2670-2682
Abstract Thiadiazoles are among the privileged pharmacological building blocks due to their unique chemical properties for diverse biological and clinical applications. 1,2,4-Thiadiazole derivatives have recently attained a therapeutic and economic importance that they did not possess a few years ago, thus leading to growing interest in this class of heterocycles. Moreover, the importance of such molecules is not restricted to medicinal chemistry; they also perform well as N,S ligands in coordination chemistry or as important intermediates for fine-chemicals synthesis. In this context, this review systematizes the main advances in the synthesis of 1,2,4-thiadiazole-based compounds in the last ten years and discloses some relevant applications of these compounds during that period.
DOI http://dx.doi.org/10.1002/ejoc.201601642
ISBN
Publisher
Book Title
ISSN 1434-193X
EISSN 1099-0690
Conference Name
Bibtex ID ISI:000403672100001
Observations
Back to Publications List