Publication Type Journal Article
Title Saccharin guanidination via facile three-component two saccharins-one dialkylcyanamide integration
Authors Alexey Yu. Dubovtsev Daniil M. Ivanov Uladzislava Dabranskaya Nadezhda A. Bokach V. Yu. Kukushkin
Groups CCC
Journal NEW JOURNAL OF CHEMISTRY
Year 2019
Month July
Volume 43
Number 27
Pages 10685-10688
Abstract Saccharin (SacH) reacts with the dialkylcyanamides NCNR2 (R-2 = Me-2, Et-2, C4H8, C5H10, and C4H8O) to grant the guanidinated saccharin derivatives Sac-C(C6H4-2-SO3-H)NC+(NH2)NR2 (65-91\%) generated via three-component integration; this type of reactivity has never been observed before for saccharin or any of the nitrile substrates.
DOI http://dx.doi.org/10.1039/c9nj02656h
ISBN
Publisher
Book Title
ISSN 1144-0546
EISSN 1369-9261
Conference Name
Bibtex ID ISI:000474646200003
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