Publication Type Journal Article
Title Manganese-Catalyzed Hydrogenation of Ketones under Mild and Base-free Conditions
Authors Stefan Weber Julian Bruenig Luis F. Veiros Karl Kirchner
Groups IOARC
Journal ORGANOMETALLICS
Year 2021
Month May
Volume 40
Number 9
Pages 1388-1394
Abstract In this paper, several Mn(I) complexes were applied as catalysts for the homogeneous hydrogenation of ketones. The most active precatalyst is the bench-stable alkyl bisphosphine Mn(I) complexfac-[Mn(dippe) (CO)(3)(CH2CH2CH3)]. The reaction proceeds at room temperature under base-free conditions with a catalyst loading of 3 mol \% and a hydrogen pressure of 10 bar. A temperature-dependent selectivity for the reduction of alpha,beta-unsaturated carbonyls was observed. At room temperature, the carbonyl group was selectively hydrogenated, while the C=C bond stayed intact. At 60 degrees C, fully saturated systems were obtained. A plausible mechanism based on DFT calculations which involves an inner-sphere hydride transfer is proposed.
DOI http://dx.doi.org/10.1021/acs.organomet.1c00161
ISBN
Publisher
Book Title
ISSN 0276-7333
EISSN 1520-6041
Conference Name
Bibtex ID ISI:000651063700024
Observations
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