Monitoring abacavir bioactivation in humans: Screening for an aldehyde metabolite
TOXICOLOGY LETTERS, 219, 59-64 5 2013
Nadia M. Grilo , Alexandra Maria Moita Antunes , Umbelina Caixas , Aline T. Marinho , Catarina Sofia Romão Charneira , M. Conceição Oliveira , Emlia C. Monteiro , M. Matilde Marques , Sofia A. Pereira

2 -Deoxythymidine Adducts from the Anti-HIV Drug Nevirapine
MOLECULES, 18, 4955-4971 5 2013
Alexandra Maria Moita Antunes , Benjamin Wolf , M. Conceição Oliveira , Frederick A. Beland , M. Matilde Marques

The role of competitive binding to human serum albumin on efavirenz-warfarin interaction: a nuclear magnetic resonance study
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 42, 443-446 11 2013
Riccardo Wanke , Shrika G. Harjivan , Sofia A. Pereira , M. Matilde Marques , Alexandra Maria Moita Antunes

Gabapentin Coordination Networks: Mechanochemical Synthesis and Behavior under Shelf Conditions
CRYSTAL GROWTH \& DESIGN, 13, 5007-5017 11 2013
Silvia Quaresma , Vânia André , Alexandra Maria Moita Antunes , Luis Cunha-Silva , M. Teresa Duarte

Synthesis and Biological Activity of 6-Selenocaffeine: Potential Modulator of Chemotherapeutic Drugs in Breast Cancer Cells
MOLECULES, 18, 5251-5264 5 2013
Inês Sofia Lança Martins , Joana P. Miranda , Nuno G. Oliveira , Ana S. Fernandes , Sandrina Goncalves , Alexandra Maria Moita Antunes

Hemoglobin adducts from the antiretroviral abacavir in HIV-infected patients as evidence of bioactivation
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 244, 8 2012
Nadia M. Grilo , Alexandra Maria Moita Antunes , Umbelina Caixas , Sandra Gouveia , M. Conceição Oliveira , Aline T. Marinho , Emilia C. Monteiro , M. Matilde Marques , Sofia A. Pereira

Oxidation of phenolic nevirapine metabolites to a reactive quinone - a plausible pathway to toxicity
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 244, 8 2012
David A. Novais , Shrika G. Harjivan , Riccardo Wanke , Pedro F. Pinheiro , Pedro P. Santos , Frederick A. Beland , M. Matilde Marques , Alexandra Maria Moita Antunes

Binding of the anti-HIV drug Efavirenz to human serum albumin: A F-19-NMR study
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 244, 8 2012
Riccardo Wanke , Shrika G. Harjivan , M. Matilde Marques , Alexandra Maria Moita Antunes

Biomimetic oxidation of aromatic xenobiotics: synthesis of the phenolic metabolites from the anti-HIV drug efavirenz
ORGANIC \& BIOMOLECULAR CHEMISTRY, 10, 4554-4561 2012
Riccardo Wanke , David A. Novais , Shrika G. Harjivan , M. Matilde Marques , Alexandra Maria Moita Antunes

Evidence for nevirapine bioactivation in man: Searching for the first step in the mechanism of nevirapine toxicity
TOXICOLOGY, 301, 33-39 11 2012
Umbelina Caixas , Alexandra Maria Moita Antunes , Aline T. Marinho , Ana L. A. Godinho , Nadia M. Grilo , M. Matilde Marques , M. Conceição Oliveira , Teresa Branco , Emilia C. Monteiro , Sofia A. Pereira

Oxidation of 2-Hydroxynevirapine, a Phenolic Metabolite of the Anti-HIV Drug Nevirapine: Evidence for an Unusual Pyridine Ring Contraction
MOLECULES, 17, 2616-2627 3 2012
Alexandra Maria Moita Antunes , Muna Sidarus , David A. Novais , Shrika G. Harjivan , P P Santos , João Ferreira da Silva , Frederick A. Beland , M. Matilde Marques

N-terminal valine adduct from the anti-HIV drug abacavir in rat haemoglobin as evidence for abacavir metabolism to a reactive aldehyde in vivo
BRITISH JOURNAL OF PHARMACOLOGY, 167, 1353-1361 11 2012
Catarina Sofia Romão Charneira , N. M. Grilo , S. A. Pereira , A. L. A. Godinho , E. C. Monteiro , M. Matilde Marques , Alexandra Maria Moita Antunes

Nevirapine metabolism to 4-formyl-nevirapine: Possible role in nevirapine toxicity
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 242, 8 2011
Alexandra Maria Moita Antunes , Ana L. A. Godinho , Sofia A. Pereira , Gordon Surratt , Goncalo Gamboa da Costa , Frederick A. Beland , M. Matilde Marques

Computational assessment of the potential role of chalcogenated flavonoids as antioxidants, enzyme inhibitors and cell signalling modulators via computational analysis
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 242, 8 2011
Alexandra Maria Moita Antunes , Gonçalo C. Justino , Inês Sofia Lança Martins , Catarina Sofia Romão Charneira , M. Matilde Marques

Reactive Aldehyde Metabolites from the Anti-HIV Drug Abacavir: Amino Acid Adducts as Possible Factors in Abacavir Toxicity
CHEMICAL RESEARCH IN TOXICOLOGY, 24, 2129-2141 12 2011
Catarina Sofia Romão Charneira , Ana L. A. Godinho , M. Conceição Oliveira , Sofia A. Pereira , Emilia C. Monteiro , M. Matilde Marques , Alexandra Maria Moita Antunes

Synthesis and oxidation of 2-hydroxynevirapine, a metabolite of the HIV reverse transcriptase inhibitor nevirapine
ORGANIC \& BIOMOLECULAR CHEMISTRY, 9, 7822-7835 2011
Alexandra Maria Moita Antunes , David A. Novais , João Ferreira da Silva , P P Santos , M. Conceição Oliveira , Frederick A. Beland , M. Matilde Marques

Amino Acid Adduct Formation by the Nevirapine Metabolite, 12-Hydroxynevirapine-A Possible Factor in Nevirapine Toxicity
CHEMICAL RESEARCH IN TOXICOLOGY, 23, 888-899 5 2010
Alexandra Maria Moita Antunes , Ana L. A. Godinho , Inês Sofia Lança Martins , Gonçalo C. Justino , Frederick A. Beland , M. Matilde Marques

Microwave-based methodology for the preparation of organoselenium compounds
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 240, 8 2010
M. Matilde Marques , Inês Sofia Lança Martins , Catarina Sofia Romão Charneira , Abel J. S. C. Vieira , Alexandra Maria Moita Antunes

Protein adduct formation: A possible factor in hypersensitivity reactions induced by the anti HIV drug abacavir
TOXICOLOGY LETTERS, 196, S110 7 2010
M. Matilde Marques , Catarina Sofia Romão Charneira , Alexandra Maria Moita Antunes

Synthesis and Oxidation of 2-Hydroxynevirapine, a Metabolite of the HIV-1 Reverse Transcriptase Inhibitor Nevirapine
CHEMICAL RESEARCH IN TOXICOLOGY, 23, 284-285 1 2010
Alexandra Maria Moita Antunes , Muna C. Sidarus , Frederick A. Beland , M. Matilde Marques