Publications

Journal Article

Exploring the therapeutic potential of Cu(II)-complexes with ligands derived from pyridoxal
INORGANICA CHIMICA ACTA, 507, 7 2020
Patrique Nunes , Fernanda M. Marques , Isabel Cavaco , J.C. Pessoa , Isabel Correia

Novel ruthenium cyclopentadienyl - peptide conjugate complexes against human FGFR(+) breast cancer
DALTON TRANSACTIONS, 49, 5974-5987 5 2020
J. Franco Machado , Miguel Machuqueiro , Fernanda M. Marques , M. Paula Robalo , M.Fatima M.Piedade , M. Helena Garcia , Joao D. G. Correia , Tânia S. Morais

Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 163, 853-863 2 2019
Leonor Côrte-Real , Brittany Karas , Patricia Girio , Alexis Moreno , Fernando Avecilla , Fernanda M. Marques , Brian T. Buckley , Keith R. Cooper , Cathleen Doherty , Pierre Falson , M. Helena Garcia , Andreia Valente

Lanthanide complexes with phenanthroline-based ligands: insights into cell death mechanisms obtained by microscopy techniques
DALTON TRANSACTIONS, 48, 4611-4624 4 2019
Maria Paula C. Campello , E Palma , Isabel Correia , Pedro M. R. Paulo , Antonio Matos , Jose Rino , Joana Coimbra , J.C. Pessoa , Dinorah Gambino , Antonio Paulo , Fernanda M. Marques

First heterobimetallic Cu(i)-dppf complexes designed for anticancer applications: synthesis, structural characterization and cytotoxicity
NEW JOURNAL OF CHEMISTRY, 43, 12308-12317 8 2019
Catarina Bravo , M. Paula Robalo , Fernanda M. Marques , Alexandra R. Fernandes , Diogo A. Sequeira , M. Fatima M. Piedade , M. Helena Garcia , Maria J. Villa de Brito , Tânia S. Morais

Polymer ruthenium-cyclopentadienyl conjugates - New emerging anti-cancer drugs
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 168, 373-384 4 2019
Tiago Moreira , Rita Francisco , Elisabeta Comsa , Sophie Duban-Deweer , Valerie Labas , Ana-Paula Teixeira-Gomes , Lucie Combes-Soia , Fernanda M. Marques , Antonio Matos , Audrey Favrelle , Cyril Rousseau , Philippe Zinck , Pierre Falson , M. Helena Garcia , Ana Preto , Andreia Valente

Antitumour and Toxicity Evaluation of a Ru(II)-Cyclopentadienyl Complex in a Prostate Cancer Model by Imaging Tools
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 19, 1262-1275 2019
Lurdes Gano , Teresa Pinheiro , Antonio P. Matos , Francisco Tortosa , Tiago F. Jorge , Maria S. Goncalves , Marta Martins , Tânia S. Morais , Andreia Valente , Ana Isabel Tomaz , Maria H. Garcia , Fernanda M. Marques

Methyl-cyclopentadienyl Ruthenium Compounds with 2,2?-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential
Inorganic Chemistry, , 4 2018
Leonor Côrte-Real , Ricardo G. Teixeira , Patricia Girio , Elisabeta Comsa , Alexis Moreno , Rachad Nasr , Hélène Baubichon-Cortay , Fernando Avecilla , Fernanda M. Marques , M Paula Robalo , Paulo Mendes , Joao P. Prates Ramalho , M. Helena Garcia , Pierre Falson , Andreia Valente

Important cytotoxic and cytostatic effects of new copper(I)-phosphane compounds with N,N, N,O and N,S bidentate ligands
DALTON TRANSACTIONS, 47, 7819-7829 6 2018
Tânia S. Morais , Yann Jousseaume , M.Fatima M.Piedade , Catarina Roma-Rodrigues , A.R. Fernandes , Fernanda M. Marques , Maria J. Villa de Brito , M. Helena Garcia

Metallacarboranes on the Road to Anticancer Therapies: Cellular Uptake, DNA Interaction, and Biological Evaluation of Cobaltabisdicarbollide [COSAN](-)
CHEMISTRY-A EUROPEAN JOURNAL, 24, 17239-17254 11 2018
Isabel Fuentes , Tania Garcia-Mendiola , Shinichi Sato , Marcos Pita , Hiroyuki Nakamura , Encarnacion Lorenzo , Francesc Teixidor , Fernanda M. Marques , Clara Vinas

Search for cytotoxic compounds against ovarian cancer cells: Synthesis, characterization and assessment of the activity of new camphor carboxylate and camphor carboxamide silver complexes
JOURNAL OF INORGANIC BIOCHEMISTRY, 188, 88-95 11 2018
M Fernanda NN Carvalho , Ana M. Botelho do Rego , Adelino M. Galvão , Rudolf Herrmann , Fernanda M. Marques

Ru-II(p-cymene) Compounds as Effective and Selective Anticancer Candidates with No Toxicity in Vivo
INORGANIC CHEMISTRY, 57, 13150-13166 11 2018
Oscar A. Lenis-Rojas , M Paula Robalo , Ana Isabel Tomaz , Andreia Carvalho , A.R. Fernandes , Fernanda M. Marques , Monica Folgueira , Julian Yanez , Digna Vazquez-Garcia , Margarita Lopez Torres , Alberto Fernandez , Jesus J. Fernandez

New copper(I) and heteronuclear copper(I)-ruthenium(II) complexes: Synthesis, structural characterization and cytotoxicity
JOURNAL OF INORGANIC BIOCHEMISTRY, 169, 68-78 4 2017
Joao Lopes , David Alves , Tânia S. Morais , Paulo J. Costa , M.Fatima M.Piedade , Fernanda M. Marques , Maria J. Villa de Brito , M. Helena Garcia

Studies on the mechanism of action of antitumor bis(aminophenolate) ruthenium(III) complexes
JOURNAL OF INORGANIC BIOCHEMISTRY, 168, 27-37 3 2017
Orsolya Doemoetoer , R. F. M. de Almeida , Leonor Côrte-Real , Cristina P. Matos , Fernanda M. Marques , Antonio Matos , Carla Real , Tamas Kiss , Eve Anna Enyedy , M. Helena Garcia , Ana Isabel Tomaz

Synthesis of Ag(I) camphor sulphonylimine complexes and assessment of their cytotoxic properties against cisplcitin-resistant A2780cisR and A2780 cell lines
JOURNAL OF INORGANIC BIOCHEMISTRY, 166, 55-63 1 2017
Joao M. S. Cardoso , Isabel Correia , Adelino M. Galvão , Fernanda M. Marques , M Fernanda NN Carvalho

New Cu(II) complexes with pyrazolyl derived Schiff base ligands: Synthesis and biological evaluation
JOURNAL OF INORGANIC BIOCHEMISTRY, 174, 63-75 9 2017
Nádia Ribeiro , Somnath Roy , Nataliya Butenko , Isabel Cavaco , Teresa Pinheiro , Irina Alho , Fernanda M. Marques , Fernando Avecilla , J.C. Pessoa , Isabel Correia

Interaction of [(VO)-O-IV(acac)(2)] with Human Serum Transferrin and Albumin
CHEMISTRY-AN ASIAN JOURNAL, 12, 2062-2084 8 2017
Isabel Correia , Ielyzaveta Chorna , Isabel Cavaco , Somnath Roy , Maxim L. Kuznetsov , Nádia Ribeiro , Gonçalo C. Justino , Fernanda M. Marques , Teresa Santos-Silva , Marino F.A. Santos , M. Santos E. Hugo , Jose L. Capelo , James Doutch , J.C. Pessoa

In Vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 17, 126-136 2017
Nuno Mendes , Francisco Tortosa , Andreia Valente , Fernanda M. Marques , Antonio Matos , Tânia S. Morais , Ana Isabel Tomaz , Fatima Gartner , M. Helena Garcia

Synthesis and Biological Evaluation of Novel 2-Aryl Benzimidazoles as Chemotherapeutic Agents
JOURNAL OF HETEROCYCLIC CHEMISTRY, 54, 255-267 1 2017
Goreti Ribeiro Morais , E Palma , Fernanda M. Marques , Lurdes Gano , Maria Cristina Oliveira , Antero J. Abrunhosa , Hugo Vicente Miranda , Tiago F. Outeiro , Isabel Santos , Antonio Paulo

Evaluation of cellular uptake, cytotoxicity and cellular ultrastructural effects of heteroleptic oxidovanadium(IV) complexes of salicylaldimines and polypyridyl ligands
JOURNAL OF INORGANIC BIOCHEMISTRY, 166, 162-172 1 2017
Gonzalo Scalese , Isabel Correia , Julio Benitez , Santiago Rostan , Fernanda M. Marques , Filipa Mendes , Antonio Pedro Matos , J.C. Pessoa , Dinorah Gambino

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