Open tubular columns containing the immobilized ligand binding domain of peroxisome proliferator-activated receptors alpha and gamma for dual agonists characterization by frontal affinity chromatography with mass spectrometry detection
JOURNAL OF CHROMATOGRAPHY A, 1284, 36-43 4 2013
C. Temporini , G. Pochetti , Giuseppe Fracchiolla , Luca Piemontese , R. Montanari , R. Moaddel , A. Laghezza , F. Altieri , L. Cervoni , D. Ubiali , E. Prada , F. Loiodice , G. Massolini , E. Calleri

New 2-(Aryloxy)-3-phenylpropanoic Acids as Peroxisome Proliferator-Activated Receptor alpha/gamma Dual Agonists Able To Upregulate Mitochondrial Carnitine Shuttle System Gene Expression
JOURNAL OF MEDICINAL CHEMISTRY, 56, 60-72 1 2013
A. Laghezza , G. Pochetti , Antonio Lavecchia , Giuseppe Fracchiolla , S. Faliti , Luca Piemontese , C. Di Giovanni , Vito Iacobazzi , Vittoria Infantino , R. Montanari , D. Capelli , P. Tortorella , F. Loiodice

Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors alpha/gamma dual agonists
BIOORGANIC \& MEDICINAL CHEMISTRY, 20, 2141-2151 3 2012
Giuseppe Fracchiolla , Antonio Laghezza , Luca Piemontese , Mariagiovanna Parente , Antonio Lavecchia , Giorgio Pochetti , Roberta Montanari , Carmen Di Giovanni , Giuseppe Carbonara , Paolo Tortorella , Ettore Novellino , Fulvio Loiodice

Frontal affinity chromatography with MS detection of the ligand binding domain of PPAR gamma receptor: Ligand affinity screening and stereoselective ligand-macromolecule interaction
JOURNAL OF CHROMATOGRAPHY A, 1232, 84-92 4 2012
E. Calleri , Giuseppe Fracchiolla , R. Montanari , G. Pochetti , Antonio Lavecchia , F. Loiodice , A. Laghezza , Luca Piemontese , G. Massolini , C. Temporini

Synthesis, Characterization and Biological Evaluation of Ureidofibrate-Like Derivatives Endowed with Peroxisome Proliferator-Activated Receptor Activity
JOURNAL OF MEDICINAL CHEMISTRY, 55, 37-54 1 2012
L. Porcelli , F. Gilardi , A. Laghezza , Luca Piemontese , N. Mitro , A. Azzariti , F. Altieri , L. Cervoni , Giuseppe Fracchiolla , M. Giudici , U. Guerrini , Antonio Lavecchia , R. Montanari , C. Di Giovanni , A. Paradiso , G. Pochetti , G. M. Simone , P. Tortorella , M. Crestani , F. Loiodice

CONVENIENT SYNTHESIS OF SOME 3-PHENYL-1-BENZOFURAN-2-CARBOXYLIC ACID DERIVATIVES AS NEW POTENTIAL INHIBITORS OF CLC-Kb CHANNELS
HETEROCYCLES, 81, 2865-2872 12 2010
Luca Piemontese , Giuseppe Carbonara , Giuseppe Fracchiolla , Antonio Laghezza , Paolo Tortorella , Fulvio Loiodice

Comparative LC Enantioseparation of Novel PPAR Agonists on Cellulose- and Amylose-Based Chiral Stationary Phases
CHROMATOGRAPHIA, 70, 1327-1333 11 2009
Luca Piemontese , Salvatore Faliti , Giuseppe Carbonara , Antonio Laghezza , Paolo Tortorella , Fulvio Loiodice

New 2-Aryloxy-3-phenyl-propatioic Acids As Peroxisome Proliferator-Activated Receptors alpha/gamma Dual Agonists with Improved Potency and Reduced Adverse Effects on Skeletal Muscle Function
JOURNAL OF MEDICINAL CHEMISTRY, 52, 6382-6393 10 2009
Giuseppe Fracchiolla , Antonio Laghezza , Luca Piemontese , Paolo Tortorella , Fernando Mazza , Roberta Montanari , Giorgio Pochetti , Antonio Lavecchia , Ettore Novellino , Sabata Pierno , Diana Conte Camerino , Fulvio Loiodice

Comparative analysis of enantioselective separation of novel PPAR agonists by HPLC on cellulose- and amylose-based chiral stationary phases
ARKIVOC, , 265-280 2009
Luca Piemontese , Salvatore Faliti , Giuseppe Carbonara , Giuseppe Fracchiolla , Paolo Tortorella , Fulvio Loiodice

Synthesis, biological evaluation, and molecular modeling investigation of chiral 2-(4-chloro-phenoxy)-3-phenyl-propanoic acid derivatives with PPAR alpha and PPAR gamma agonist activity
BIOORGANIC \& MEDICINAL CHEMISTRY, 16, 9498-9510 11 2008
Giuseppe Fracchiolla , Antonio Lavecchia , Antonio Laghezza , Luca Piemontese , Raffaella Trisolini , Giuseppe Carbonara , Paolo Tortorella , Ettore Novellino , Fulvio Loiodice

Synthesis, biological evaluation, and molecular modeling investigation of chiral phenoxyacetic acid analogues with PPAR alpha and PPAR gamma agonist activity
CHEMMEDCHEM, 2, 641-654 5 2007
Giuseppe Fracchiolla , Antonio Laghezza , Luca Piemontese , Giuseppe Carbonara , Antonio Lavecchia , Paolo Tortorella , Maurizio Crestani , Ettore Novellino , Fulvio Loiodice

Occurrence of patulin in conventional and organic fruit products in Italy and subsequent exposure assessment
FOOD ADDITIVES AND CONTAMINANTS, 22, 437-442 5 2005
Luca Piemontese , M Solfrizzo , A Visconti