First heterobimetallic Cu(i)-dppf complexes designed for anticancer applications: synthesis, structural characterization and cytotoxicity
NEW JOURNAL OF CHEMISTRY, 43, 12308-12317 8 2019
Catarina Bravo , M. Paula Robalo , Fernanda M. Marques , Alexandra R. Fernandes , Diogo A. Sequeira , M. Fatima M. Piedade , M. Helena Garcia , Maria J. Villa de Brito , Tânia S. Morais

Ruthenium-Cyclopentadienyl Bipyridine-Biotin Based Compounds: Synthesis and Biological Effect
INORGANIC CHEMISTRY, 58, 9135-9149 7 2019
Leonor Côrte-Real , Brittany Karas , Ana Rita Brás , Adhan Pilon , Fernando Avecilla , Fernanda Marques , Ana Preto , Brian T. Buckley , Keith R. Cooper , Cathleen Doherty , M. Helena Garcia , Andreia Valente

Polymer ruthenium-cyclopentadienyl conjugates - New emerging anti-cancer drugs
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 168, 373-384 4 2019
Tiago Moreira , Rita Francisco , Elisabeta Comsa , Sophie Duban-Deweer , Valerie Labas , Ana-Paula Teixeira-Gomes , Lucie Combes-Soia , Fernanda M. Marques , Antonio Matos , Audrey Favrelle , Cyril Rousseau , Philippe Zinck , Pierre Falson , M. Helena Garcia , Ana Preto , Andreia Valente

Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 163, 853-863 2 2019
Leonor Côrte-Real , Brittany Karas , Patricia Girio , Alexis Moreno , Fernando Avecilla , Fernanda M. Marques , Brian T. Buckley , Keith R. Cooper , Cathleen Doherty , Pierre Falson , M. Helena Garcia , Andreia Valente

Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorinated ligand shows strong activity towards colorectal cancer cells
European Journal of Medicinal Chemistry , 143, 503-514 2018
Ricardo G. Teixeira , Ana Rita Brás , Leonor Côrte-Real , Rajendhraprasad Tatikonda , Anabela Sanches , M Paula Robalo , Fernado Avecilla , Tiago Moreira , M. Helena Garcia , Matti Haukka , Ana Preto , Andreia Valente

Methyl-cyclopentadienyl Ruthenium Compounds with 2,2?-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential
Inorganic Chemistry, , 4 2018
Leonor Côrte-Real , Ricardo G. Teixeira , Patricia Girio , Elisabeta Comsa , Alexis Moreno , Rachad Nasr , Hélène Baubichon-Cortay , Fernando Avecilla , Fernanda M. Marques , M Paula Robalo , Paulo Mendes , Joao P. Prates Ramalho , M. Helena Garcia , Pierre Falson , Andreia Valente

Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorinated ligand shows strong activity towards colorectal cancer cells
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 143, 503-514 1 2018
Ricardo G. Teixeira , Ana Rita Brás , Leonor Côrte-Real , Rajendhraprasad Tatikonda , Anabela Sanches , M Paula Robalo , Fernando Avecilla , Tiago Moreira , M. Helena Garcia , Matti Haukka , Ana Preto , Andreia Valente

Important cytotoxic and cytostatic effects of new copper(I)-phosphane compounds with N,N, N,O and N,S bidentate ligands
DALTON TRANSACTIONS, 47, 7819-7829 6 2018
Tânia S. Morais , Yann Jousseaume , M.Fatima M.Piedade , Catarina Roma-Rodrigues , A.R. Fernandes , Fernanda M. Marques , Maria J. Villa de Brito , M. Helena Garcia

Studies on the mechanism of action of antitumor bis(aminophenolate) ruthenium(III) complexes
JOURNAL OF INORGANIC BIOCHEMISTRY, 168, 27-37 3 2017
Orsolya Doemoetoer , R. F. M. de Almeida , Leonor Côrte-Real , Cristina P. Matos , Fernanda M. Marques , Antonio Matos , Carla Real , Tamas Kiss , Eve Anna Enyedy , M. Helena Garcia , Ana Isabel Tomaz

New copper(I) and heteronuclear copper(I)-ruthenium(II) complexes: Synthesis, structural characterization and cytotoxicity
JOURNAL OF INORGANIC BIOCHEMISTRY, 169, 68-78 4 2017
Joao Lopes , David Alves , Tânia S. Morais , Paulo J. Costa , M.Fatima M.Piedade , Fernanda M. Marques , Maria J. Villa de Brito , M. Helena Garcia

In Vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 17, 126-136 2017
Nuno Mendes , Francisco Tortosa , Andreia Valente , Fernanda M. Marques , Antonio Matos , Tânia S. Morais , Ana Isabel Tomaz , Fatima Gartner , M. Helena Garcia

New iron cyclopentadienyl complexes bearing different phosphane co-ligands: Structural factors vs. cytotoxicity
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 852, 34-42 12 2017
Adhan Pilon , Patricia Girio , Guilherme Nogueira , Fernando Avecilla , Harry Adams , Julia Lorenzo , M. Helena Garcia , Andreia Valente

eta(6)-(2-phenoxyethanol) ruthenium(II)-complexes of 2,2 -bipyridine and its derivatives: Solution speciation and kinetic behaviour
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 820, 20-29 10 2016
Guilherme Nogueira , Orsolya Domotor , Adhan Pilon , M Paula Robalo , Fernando Avecilla , M. Helena Garcia , Eva A. Enyedy , Andreia Valente

Tracking antitumor metallodrugs: promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds
FUTURE MEDICINAL CHEMISTRY, 8, 527-544 2016
Tânia S. Morais , Andreia Valente , Ana Isabel Tomaz , Fernanda M. Marques , M. Helena Garcia

Novel ruthenium(II) cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasites
JOURNAL OF INORGANIC BIOCHEMISTRY, 153, 306-314 12 2015
Mariana Fernandez , Esteban Rodriguez Arce , Cynthia Sarniguet , Tânia S. Morais , Ana Isabel Tomaz , Claudio Olea Azar , Roberto Figueroa , J. Diego Maya , Andrea Medeiros , Marcelo Comini , M. Helena Garcia , Lucia Otero , Dinorah Gambino

The key role of coligands in novel ruthenium(II)-cyclopentadienyl bipyridine derivatives: Ranging from non-cytotoxic to highly cytotoxic compounds
JOURNAL OF INORGANIC BIOCHEMISTRY, 150, 148-159 9 2015
Leonor Côrte-Real , M Paula Robalo , Fernanda M. Marques , Guilherme Nogueira , Fernando Avecilla , Tiago J. L. Silva , Filipa C. Santos , Ana Isabel Tomaz , M. Helena Garcia , Andreia Valente

A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites
JOURNAL OF COORDINATION CHEMISTRY, 68, 2923-2937 2015
Esteban Rodriguez Arce , Cynthia Sarniguet , Tania S. Moraes , Marisol Vieites , Ana Isabel Tomaz , Andrea Medeiros , Marcelo A. Comini , Javier Varela , Hugo Cerecetto , Mercedes Gonzalez , Fernanda M. Marques , M. Helena Garcia , Lucia Otero , Dinorah Gambino

Mono(eta(5)-cyclopentadienyl)metal(II) Complexes with Thienyl Acetylide Chromophores: Synthesis, Electrochemical Studies, and First Hyperpolarizabilities
ORGANOMETALLICS, 33, 4655-4671 9 2014
Tiago J. L. Silva , Paulo Mendes , Ana M. Santos , M. Helena Garcia , M Paula Robalo , J. P. Prates Ramalho , A. J. Palace Carvalho , Marina Buechert , Christian Wittenburg , Juergen Heck

New iron(II) cyclopentadienyl derivative complexes: Synthesis and antitumor activity against human leukemia cancer cells
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 756, 52-60 4 2014
Andreia Valente , Ana Margarida Santos , Leonor Côrte-Real , M Paula Robalo , Virtudes Moreno , Merce Font-Bardia , Teresa Calvet , Julia Lorenzo , M. Helena Garcia

New water-soluble ruthenium(II) cytotoxic complex: Biological activity and cellular distribution
JOURNAL OF INORGANIC BIOCHEMISTRY, 130, 1-14 1 2014
Tânia S. Morais , Filipa C. Santos , Tiago F. Jorge , Leonor Côrte-Real , Paulo J. Amorim Madeira , Fernanda M. Marques , M Paula Robalo , Antonio Matos , Isabel Santos , M. Helena Garcia