Publications

Journal Article

Novel dodecyl-containing azido and glucuronamide-based nucleosides exhibiting anticancer potential
PURE AND APPLIED CHEMISTRY, 91, 1085–1105 2019
Nuno Manuel Xavier , Rita Goncalves-Pereira , Radek Jorda , Denisa Hendrychová , M. Conceição Oliveira

Synthesis and biological evaluation of structurally varied 5´-/6´-isonucleosides and theobromine-containing N-isonucleosidyl derivatives
PHARMACEUTICALS, 12, 103 2019
Nuno Manuel Xavier , Eduardo C. de Sousa , Margarida P. Pereira , Anne Loesche , Immo Serbian , Rene Csuk , M. Conceição Oliveira

2-Deoxyglycosylation towards more effective and bioavailable neuroprotective molecules inspired by nature
PURE AND APPLIED CHEMISTRY, 91, 1209-1221 7 2019
Catarina Dias , Ana M. Matos , Maria T. Blasquez-Sanchez , Patricia Calado , Alice Martins , Philipp Datwyler , Beat Ernst , Maria Paula de Macedo , Nicola Colabufo , Amélia P. Rauter

Assessing the Optimal Deoxygenation Pattern of Dodecyl Glycosides for Antimicrobial Activity Against Bacillus anthracis
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, , 2224-2233 3 2019
Catarina Dias , Alice Martins , Ana Pelerito , Maria C. Oliveira , Marialessandra Contino , Nicola A. Colabufo , Amélia P. Rauter

Biological properties of phenolic compound extracts in selected Algerian honeys-The inhibition of acetylcholinesterase and alpha-glucosidase activities
EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE, 25, 77-84 1 2019
Hicham Zaidi , Salim Ouchemoukh , Nadia Amessis-Ouchemoukh , Nadjet Debbache , Rita Pacheco , Maria L. Serralheiro , M. Eduarda Araújo

Bridging Type 2 Diabetes and Alzheimer s Disease: Assembling the Puzzle Pieces in the Quest for the Molecules With Therapeutic and Preventive Potential
MEDICINAL RESEARCH REVIEWS, 38, 261-324 1 2018
Ana Marta de Matos , Maria Paula de Macedo , Amélia P. Rauter

Sugar-based bactericides targeting phosphatidylethanolamine-enriched membranes
NATURE COMMUNICATIONS, 9, 11 2018
Catarina Dias , Joao P. Pais , Rafael Nunes , Maria-Teresa Blazquez-Sanchez , J. T. Marques , Andreia F. Almeida , Patricia Serra , Nuno Manuel Xavier , Diogo Vila-Vicosa , Miguel Machuqueiro , A. Viana , Alice Martins , M. Soledade C. S. Santos , Ana Pelerito , Ricardo Dias , Rogerio Tenreiro , M. Conceição Oliveira , Marialessandra Contino , Nicola A. Colabufo , R. F. M. de Almeida , Amélia P. Rauter

Nomenclature of flavonoids (IUPAC Recommendations 2017)
PURE AND APPLIED CHEMISTRY, 90, 1429-1486 9 2018
Amélia P. Rauter , Marcus Ennis , Karl-Heinz Hellwich , Bernardo J. Herold , Derek Horton , Gerard P. Moss , Ida Schomburg

Proactive response to tackle the threat of emerging drugs: Synthesis and toxicity evaluation of new cathinones
FORENSIC SCIENCE INTERNATIONAL, 290, 146-156 9 2018
Helena Gaspar , Soraia Bronze , Catarina Oliveira , Bruno L. Victor , Miguel Machuqueiro , R Pacheco , Maria Joao Caldeira , Susana Santos

Furanosyl Nucleoside Analogues Embodying Triazole or Theobromine Units as Potential Lead Molecules for Alzheimer s Disease
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, , 2667-2681 6 2018
Rita Goncalves-Pereira , Margarida P. Pereira , Sofia G. Serra , Anne Loesche , Rene Csuk , Samuel Silvestre , Paulo J. Costa , M. Conceição Oliveira , Nuno Manuel Xavier

Vegetable Tannins Used in the Manufacture of Historic Leathers
MOLECULES, 23, 5 2018
Lina Falcao , M. Eduarda Araújo

Choline-Amino Acid Ionic Liquids as Green Functional Excipients to Enhance Drug Solubility
PHARMACEUTICS, 10, 12 2018
Rita Caparica , Ana Julio , Andre Rolim Baby , M. Eduarda Araújo , Ana Sofia Fernandes , J. G. Costa , Tania Almeida

A double Philadelphia chromosome-positive chronic myeloid leukemia patient, co-expressing P210(BCR-ABL1) and P195(BCR-ABL1) isoforms
HAEMATOLOGICA, 103, E549-E552 10 2018
Raquel Vinhas , Alexandra Lourenco , Susana Santos , Patricia Ribeiro , Madalena Silva , Aida Botelho de Sousa , Pedro V. Baptista , A.R. Fernandes

Unlocking the in vitroanti- inflammatory and antidiabetic potential of Polygonum maritimum
PHARMACEUTICAL BIOLOGY, 55, 1348-1357 2017
Maria Joao Rodrigues , Luisa Custodio , Andreia Lopes , Marta Oliveira , N. R. Neng , J. M. F. Nogueira , Alice Martins , Amélia P. Rauter , Joao Varela , Luisa Barreira

Targeting Type 2 Diabetes with C-Glucosyl Dihydrochalcones as Selective Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitors: Synthesis and Biological Evaluation
JOURNAL OF MEDICINAL CHEMISTRY, 60, 568-579 1 2017
Ana R. Jesus , Diogo Vila-Vicosa , Miguel Machuqueiro , Ana P. Marques , Timothy M. Dore , Amélia P. Rauter

Synthesis and effects of flavonoid structure variation on amyloid-beta aggregation
PURE AND APPLIED CHEMISTRY, 89, 1305-1320 9 2017
Ana M. Matos , Joana S. Cristovao , Dmitry V. Yashunsky , Nikolay E. Nifantiev , A. Viana , Claudio M. Gomes , Amélia P. Rauter

Phytochemical Characterization and Biological Evaluation of the Aqueous and Supercritical Fluid Extracts from Salvia sclareoides Brot
OPEN CHEMISTRY, 15, 82-91 1 2017
Daniela Batista , Pedro L. Fale , Maria L. Serralheiro , M. Eduarda Araújo , Catarina Dias , Isabel Branco , Clara Grosso , José Coelho , António Palavra , Paulo J. A. Madeira , Alice Martins , Amélia P. Rauter

Antiparasitic Activity of Diterpenoids Against Trypanosoma cruzi
PLANTA MEDICA, 83, 306-311 2 2017
Sergio Alegre-Gomez , Paula Sainz , M. Fatima Simoes , Patricia Rijo , C. M. M. Moiteiro , Azucena Gonzalez-Coloma , Rafael A. Martinez-Diaz

Synthesis and antiproliferative evaluation of novel azido nucleosides and their phosphoramidate derivatives
PURE AND APPLIED CHEMISTRY, 89, 1267-1281 9 2017
Nuno Manuel Xavier , Rita Goncalves-Pereira , Radek Jorda , Eva Reznickova , Vladimir Krystof , M. Conceição Oliveira

Exploitation of new structurally diverse D-glucuronamide-containing N-glycosyl compounds: synthesis and anticancer potential
ORGANIC & BIOMOLECULAR CHEMISTRY, 15, 4667-4680 6 2017
Nuno Manuel Xavier , Alexandre Porcheron , Daniela Batista , Radek Jorda , Eva Reznickova , Vladimir Krystof , M. Conceição Oliveira

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