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  3. Tânia S. Morais

Tânia Sofia Ferreira Morais

Orcid number 0000-0003-0233-8243 Researcher id D-8824-2011

04 Bioinorganic Chemistry and Drug Development

tsmorais@fc.ul.pt Phone: 217500954 Fax: www: https://tsmorais.wixsite.com/tsmorais

Tânia Morais has a degree in Chemistry (2007) by Faculdade de Ciências da Universidade de Lisboa (FCUL), where she also completed a master's degree in Chemistry with specialization in Chemistry, Health and Nutrition (2008). Tânia Morais got her PhD in Chemistry with specialization in Inorganic Chemistry (2013) by University of Lisbon. She was honored by the Portuguese Chemical Society in 2014 with the prize “Portuguese Young Chemist Award”. She is currently a post-doctoral researcher in Centro de Química Estrutural of Faculdade de Ciências da Universidade de Lisboa, under the supervision of professor Maria Helena Garcia. Tânia Morais research focuses on the development of chemical synthesis and characterization of organic, inorganic and organometallic compounds for cancer therapy and evaluation of properties of potential drugs and their interaction with biomolecules. Has a total of 23 articles published in international journals with peer review, 3 book chapters and 3 patents.

Selected Papers

Biological activity and cellular uptake of [Ru(eta(5)-C5H5)(PPh3)(Me(2)bpy)][CF3SO3] complex
JOURNAL OF INORGANIC BIOCHEMISTRY, 122, 8-17 5 2013
Tânia S. Morais , Filipa C. Santos , Leonor Côrte-Real , Fernanda M. Marques , M Paula Robalo , Paulo J. Amorim Madeira , M. Helena Garcia

New water-soluble ruthenium(II) cytotoxic complex: Biological activity and cellular distribution
JOURNAL OF INORGANIC BIOCHEMISTRY, 130, 1-14 1 2014
Tânia S. Morais , Filipa C. Santos , Tiago F. Jorge , Leonor Côrte-Real , Paulo J. Amorim Madeira , Fernanda M. Marques , M Paula Robalo , Antonio Matos , Isabel Santos , M. Helena Garcia

Tracking antitumor metallodrugs: promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds
FUTURE MEDICINAL CHEMISTRY, 8, 527-544 2016
Tânia S. Morais , Andreia Valente , Ana Isabel Tomaz , Fernanda M. Marques , M. Helena Garcia

In Vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 17, 126-136 2017
Nuno Mendes , Francisco Tortosa , Andreia Valente , Fernanda M. Marques , Antonio Matos , Tânia S. Morais , Ana Isabel Tomaz , Fatima Gartner , M. Helena Garcia

Inhibition of cancer cell growth by ruthenium(II) cyclopentadienyl derivative complexes with heteroaromatic ligands
JOURNAL OF INORGANIC BIOCHEMISTRY, 103, 354-361 3 2009
M. Helena Garcia , Tânia S. Morais , Pedro Florindo , M.Fatima M.Piedade , Virtudes Moreno , Carlos Ciudad , Veronica Noe

New copper(I) and heteronuclear copper(I)-ruthenium(II) complexes: Synthesis, structural characterization and cytotoxicity
JOURNAL OF INORGANIC BIOCHEMISTRY, 169, 68-78 4 2017
Joao Lopes , David Alves , Tânia S. Morais , Paulo J. Costa , M.Fatima M.Piedade , Fernanda M. Marques , Maria J. Villa de Brito , M. Helena Garcia

Member publications