top_menu_en
left_menu_en
 
 
 
    Research center
    supported by the FCT
 
[Logo] FCT
 
 
 
 
 

Maxim L. Kuznetsov, Ph.D.

Konstantin V. Luzyanin

Contacts

Phone: (+351) 21-8419236
Fax: (+351) 21-8464455
E-mail: max@mail.ist.utl.pt

Brief Curriculum Vitae

BORN

September, 19th, 1971

EDUCATION

•Ph.D. in Inorganic Chemistry, Moscow State Pedagogical University (MSPU), 1996
•Higher Education (equal to MSc) with "Red Diploma" as the highest-ranking student, Chemistry, MSPU, 1988-1993

CAREER

•Senior Researcher at the Centro de Quimica Estrutural, Instituto Superior Tecnico, Lisbon, Portugal (2008-present)
•Post-doctoral researcher at the Centro de Quimica Estrutural, Instituto Superior Tecnico, Lisbon, Portugal (split with position of Associate Professor at MSPU), coordinator – Prof. Armando J. L. Pombeiro, 1998-2007
•Associate Professor at the Department of Chemistry, MSPU, Moscow, Russia, 2000–2007
•Assistant Professor at the Department of Chemistry, MSPU, Moscow, Russia, 1997-2000
•Researcher the Department of Chemistry, MSPU, Moscow, Russia, 1996–1997
•Extended courses and research practice within the post-graduate scholarship at the Laboratory of Molecular Spectroscopy, Nesmeyanov’s Institute of Organoelement Compounds, Moscow, Russia, 1995
•Post-graduate student (under supervision of Prof. A.I. Dement’ev) at the Department of Chemistry, MSPU, Moscow, Russia, 1993–1996

RESEARCH INTERESTS

Molecular catalysis. Metal-catalysed and metal-free functionalization of alkanes. Activation of CH and CC bonds


Application of theoretical methods for the investigation of plausible mechanisms and the role of the catalyst, oxidizing agent and solvent in the reactions of carboxylation, hydroxylation and halogenation of alkanes to acetic acids, alcohols, ketones and haloalkanes without a catalyst and catalysed by transition-metal complexes and metal oxides

Maxim L. Kuznetsov

Activation of small molecules by coordination to a metal centre leading to compounds with pharmacological and industrial significance


Application of theoretical methods for the investigation of the metal-assisted activation of small molecules (RCN, RNC, CO, allenes, carbenes, carbynes, etc.) containing unsaturated bonds towards nucleophilic-, electrophilic-, cyclo-additions and substitution leading to syntheses of compounds with pharmacological and industrial significance. Detailed investigations of the reaction mechanisms, estimates of kinetic and thermodynamic characteristics of the processes. Theoretical studies of solvent and substituent effects. Testing of the reliability of computational methods.

Maxim L. Kuznetsov

Maxim L. Kuznetsov

Structural, spectral, redox properties, nature of chemical bonds, molecular and electronic structures of transition metal complexes


Theoretical studies of the coordination bond nature, molecular and electronic structure, isomerization and electrochemical behaviours of nitrile, isocyanide and carbonyl transition-metal complexes and of areneruthenium(II) pyrazolonate complexes. Theoretical studies of relative stability of different isomeric forms of the products of nucleophilic additions to metal-bound organonitriles. Theoretical studies of coordination behaviours of oxazolinylferrocenes in Pd-allyl complexes and pyrazolone-5 derivatives in lanthanide complexes. Theoretical studies of electrochemical behaviours and metal–metal interactions in dinuclear hydride iron complexes with linking dinitriles. Theoretical studies of the structure, vibrational spectra and excited states of oxygen clusters of heavy metals in extremely high oxidation states.

Maxim L. Kuznetsov

Maxim L. Kuznetsov

Cycloaddition reactions


Detailed theoretical studies of “pure” organic and metal-assisted 1,3-dipolar cycloadditions of dipoles of different types to dipolarophiles bearing homo- and heteronuclear CC, CN and NN multiple bonds. Theoretical analysis of chemo-, regio- and stereoselectivity of cycloaddition reactions. Application of quantum-chemical description of the “hard-soft acids-bases” principle to the studies of cycloaddition, nucleophilic and electrophilic addition reactions.

Maxim L. Kuznetsov

Synthesis, molecular structure and coordination behaviour of pyrazolone-5 based analgesics and their complexes with rare-earth metals


Theoretical calculations of the molecular and electronic structures and spectroscopic properties of pyrazolone-5 based analgesics (amidopyrine, antipyrine, other pyrazolone-5 derivatives) and their complexes with rare-earth metals. Synthesis of the complexes of anhydrous salts of rare-earth metals with pyrazolone-5 derivatives followed by determination of their composition, coordination modes, stability (formation) constants, structural and spectral characteristics.

Maxim L. Kuznetsov

SELECTED PUBLICATIONS


1. M.V. Kirillova, A.M. Kirillov, M.L. Kuznetsov, J.A.L. Silva, J.J.R. Fraústo da Silva, A.J.L. Pombeiro. Alkanes to Carboxylic Acids in Aqueous Medium: Metal-free and Metal-promoted Highly Efficient and Mild Conversions. Chem. Commun., (2009) in press.
2. M.V. Kirillova, M.L. Kuznetsov, J.A.L. da Silva, M.F.C. Guedes da Silva, J.J.R. Frausto da Silva, A.J.L. Pombeiro. Amavadine and Other Vanadium Complexes as Remarkably Efficient Catalysts for the Single-pot Conversion of Ethane into Propionic and Acetic Acids. Chem. Eur. J., 14 (2008) 1828.
3. M.V. Kirillova, M.L. Kuznetsov, P.M. Reis, J.A.L. da Silva, J.J.R. Frausto da Silva, A.J.L. Pombeiro. Direct and Remarkably Efficient Conversion of Methane into Acetic Acid Catalazed by Amavadine and Related Vanadium Complexes. A Synthetic and a Theoretical DFT Mechanistic Study. J. Am. Chem. Soc., 129 (2007) 10531.
4. M.L. Kuznetsov, A.A. Nazarov, L.V. Kozlova, V.Yu. Kukushkin. Theoretical Study of Chemo-, Regio-, and Stereoselectivity in 1,3-Dipolar Cycloadditions of Nitrones and Nitrile Oxides to Free and Pt-Bound Bifunctional Dipolarophiles. J. Org. Chem., 72 (2007) 4475.
5. M.L. Kuznetsov, A.A. Nazarov, A.J.L. Pombeiro. Protic conversion of nitrile into azavinylidene complexes of rhenium, a mechanistic theoretical study. J. Phys. Chem. A, 109 (2005) 8187.

PUBLICATIONS IN JOURNALS

Reviews

1. M.L. Kuznetsov*, V.Yu. Kukushkin. Theoretical Studies of Cycloaddition Reactions Controlled by Lewis Acids. Russ. J. Inorg. Chem., 53 (2008) 1997–2018.
2. M.L. Kuznetsov*. Theoretical Studies on [3 + 2]-Cycloadditon Reactions. Russ. Chem. Rev., 75 (2006) 935–960.
3. M.L. Kuznetsov*. Theoretical Studies of Transition Metal Complexes with Nitriles and Isocyanides. Russ. Chem. Rev., 71 (2002) 265–282.

Articles

4. J. Kasser, A.A. Nazarov*, C.G. Hartinger*, B. Wdziekonski, C. Dani, M.L. Kuznetsov, V. Arion, B.K. Keppler. A one step/one pot synthesis of N,N-bis(phosphonomethyl)amino acids and their effects on adipogenic and osteogenic differentiation of human mesenchymal stem cells. Bioorg. Med. Chem., (2009) in press.
5. M.V. Kirillova, A.M. Kirillov, M.L. Kuznetsov, J.A.L. Silva, J.J.R. Fraústo da Silva, A.J.L. Pombeiro*. Alkanes to Carboxylic Acids in Aqueous Medium: Metal-free and Metal-promoted Highly Efficient and Mild Conversions. Chem. Commun., (2009) in press.
6. P. Adão, M.R. Maurya, U. Kumar, F. Avecilla, R.T. Henriques, M. L. Kuznetsov, J.C. Pessoa*, I. Correia*. Vanadium-salen and -salan complexes: characterization and application in oxygen transfer reactions. Pure Appl. Chem., (2009) in press.
7. P. Adão, J. Costa Pessoa*, R.T. Henriques, M.L. Kuznetsov, F. Avecilla, M.R. Maurya, U. Kumar, I. Correia*. Synthesis, Characterization, and Application of Vanadium-Salan Complexes in Oxygen Transfer Reactions. Inorg. Chem., 48 (2009) 3542.
8. M.L. Kuznetsov*, N.A. Bokach, V.Yu. Kukushkin, A.I. Dement'ev. Theoretical Study of Ammonia Nucleophilic Addition to Nitriles in Platinum Complexes. Russ. J. Gen. Chem., 79 (2009) 232.
9. P.V. Gushchin, M.L. Kuznetsov, M. Haukka, M.J. Wang, A.V. Gribanov, V.Yu. Kukushkin*. A Novel Reactivity Mode for Metal-Activated Dialkylcyanamide Species: Addition of N,N'-Diphenylguanidine to a cis-(R2NCN)2PtII Center Giving an Eight-Membered Chelated Platinaguanidine. Inorg. Chem., 48 (2009) 2583.
10. N.A. Bokach*, M.L. Kuznetsov, M. Haukka, V.I. Ovcharenko, E.V. Tretyakov, V. Yu. Kukushkin*. Platinum(II)-Complexed Tetrahydroimidazo[1,2-b][1,2,4]oxadiazoles Derived from Metal-Mediated 1,3-Dipolar Cycloaddition. Novel Type of Heterocycles, Which Do Not Exist without the Metal Center. Organometallics, 28 (2009) 1406.
11. M.L. Kuznetsov, A.J.L. Pombeiro*. Radical Formation in the [MeReO3]-Catalyzed Aqueous Peroxidative Oxidation of Alkanes: A Theoretical Mechanistic Study. Inorg. Chem., 48 (2009) 307.
12. I. Berger, M. Hanif, A.A. Nazarov*, C.G. Hartinger*, R.O. John, M.L. Kuznetsov, M. Groessl, F. Schmitt, O. Zava, F. Biba, V.B. Arion, M. Galanski, M.A. Jakupec, L. Juillerat-Jeanneret, P.J. Dyson, B.K. Keppler. In Vitro Anticancer Activity and Biologically Relevant Metabolization of Organometallic Ruthenium Complexes with Carbohydrate-Based Ligands. Chem. Eur. J., 14 (2008) 9046.
13. M.R. Tyan, N.A. Bokach*, M.J. Wang, M. Haukka, M.L. Kuznetsov, V.Yu. Kukushkin*. Facile cyanamide-ammonia coupling mediated by cis- and trans-[PtIIL2] centers and giving metal-bound. Dalton Trans., (2008) 5178.
14. M.V. Kirillova, M.L. Kuznetsov, J.A.L. da Silva, M.F.C. Guedes da Silva, J.J.R. Frausto da Silva, A.J.L. Pombeiro*. Amavadine and Other Vanadium Complexes as Remarkably Efficient Catalysts for the Single-pot Conversion of Ethane into Propionic and Acetic Acids. Chem. Eur. J., 14 (2008) 1828.
15. M.L. Kuznetsov*, V.Yu. Kukushkin, A.J.L. Pombeiro*. Reactivity of Pt- and Pd-bound nitriles toward nitrile oxides and nitrones: substitution versus cycloaddition. Dalton Trans., (2008) 1312.
16. M.V. Kirillova, M.L. Kuznetsov, P.M. Reis, J.A.L. da Silva, J.J.R. Frausto da Silva, A.J.L. Pombeiro*. Direct and Remarkably Efficient Conversion of Methane into Acetic Acid Catalazed by Amavadine and Related Vanadium Complexes. A Synthetic and a Theoretical DFT Mechanistic Study. J. Am. Chem. Soc., 129 (2007) 10531.
17.F. Marchetti*, C. Pettinari, R. Pettinari, A. Cerquetella, A. Cingolani, E.J. Chan, K. Kozawa, B.W. Skelton, A.H. White, R. Wanke, M.L. Kuznetsov, L.M.D.R.S. Martins, A.J.L. Pombeiro. Areneruthenium(II) 4-Acyl-5-pyrazolonate Derivatives: Coordination Chemistry, Redox Properties and Reactivity. Inorg. Chem., 46 (2007) 8245.
18. M.L. Kuznetsov*, A.A. Nazarov, L.V. Kozlova, V.Yu. Kukushkin. Theoretical Study of Chemo-, Regio-, and Stereoselectivity in 1,3-Dipolar Cycloadditions of Nitrones and Nitrile Oxides to Free and Pt-Bound Bifunctional Dipolarophiles. J. Org. Chem., 72 (2007) 4475.
19. K.V. Luzyanin, V.Yu. Kukushkin*, M.L. Kuznetsov, A.D. Ryabov, M. Galanski, M. Haukka, E.V. Tretyakov, V.I. Ovcharenko, M.N. Kopylovich, A.J.L. Pombeiro*. Kinetic and Thermodynamic Aspects of the Regioselective Addition of Bifunctional Hydroxylaminooxime-type HO-Nucleophiles to Pt-Complexed Nitriles. Inorg. Chem., 45 (2006) 2296.
20. M.L. Kuznetsov*, V.Yu. Kukushkin. Theoretical Study of Reactant Activation in 1,3-Dipolar Cycloadditions of Cyclic Nitrones to Free and Pt-Bound Nitriles. J. Org. Chem., 71 (2006) 582.
21.M.L. Kuznetsov, A.A. Nazarov, A.J.L. Pombeiro*. Protic conversion of nitrile into azavinylidene complexes of rhenium, a mechanistic theoretical study. J. Phys. Chem. A, 109 (2005) 8187.
22.M.L. Kuznetsov*, L.V. Kozlova, A.I. Dement’ev. Theoretical Study of 1,3-Dipolar Cycloaddition of Nitrones to Doubly Activated Nitriles. Russ. J. Inorg. Chem., 51 (2006) 1602.
23. C.G. Hartinger*, A.A. Nazarov*, V.B. Arion, G. Giester, M.L. Kuznetsov, M. Galanski, B.K. Keppler*. 1,1'-Bis(oxazolin-2-yl)ferrocenes: An Investigation of Their Complexation Behavior toward [Pd(eta3-allyl)Cl]2. Eur. J. Inorg. Chem., (2005) 1589.
24. M.L. Kuznetsov*, A.I. Dement'ev, A.A. Nazarov. Theoretical analysis of vibrational spectra and nature of coordination bond in the nitrile complexes of platinum. Russ. J. Inorg. Chem., 50 (2005) 731.
25. E.A. Klestova-Nadeeva, M.L. Kuznetsov*, A.I. Dement'ev. Theoretical study of reactions of nucleophilic addition of oximes to the nitrile complexes trans-/cis-[ReCl4(NCCH3)2]. Russ. J. Inorg. Chem., 50 (2005) 588.
26. M.L. Kuznetsov*. Is the charge on the nitrile carbon atom a driving force of the nucleophilic addition to coordinated nitriles? J. Molec. Struct. (THEOCHEM), 674 (2004) 33.
27. M.L. Kuznetsov*, E.A. Klestova-Nadeeva, A.I. Dement'ev. Theoretical study on reactivity of coordinated nitriles: structure, bonding and reactivity of [ReCl4(NCCH3)2]. J. Molec. Struct. (THEOCHEM), 671 (2004) 229.
28. M.L. Kuznetsov*, V.Yu. Kukushkin, A.I. Dementev, A.J.L. Pombeiro*. 1,3-Dipolar Cycloaddition of Nitrones to Free and Pt-Bound Nitriles. A Theoretical Study of the Activation Effect, Reactivity and Mechanism. J. Phys. Chem. A, 107 (2003) 6108.
29. M.L. Kuznetsov, A.J.L. Pombeiro. Theoretical Study of Redox Induced Isomerizations, Structure and Bonding of Nitrile, Isocyanide and Carbonyl Complexes of Rhenium. Dalton Trans., (2003) 738.
30. M.L. Kuznetsov*, V.Yu. Kukushkin*, M. Haukka, A.J.L. Pombeiro*. 1,3-Dipolar cycloaddition of nitrile oxides to free and Pt-bound nitriles: a theoretical study of the activation effect, reactivity and mechanism (special volume dedicated to retirement of Prof. J.J.R. Frausto da Silva). Inorg. Chim. Acta, 356 (2003) 85.
31. M.L. Kuznetsov, M. Haukka, A.J.L. Pombeiro*, A.A. Nazarov, V.Yu. Kukushkin*. Theoretical study of the relative stability of isomeric forms of platinum carboxamide complexes (special volume dedicated to Prof. Pierre Braunstein). Inorg. Chim. Acta, 350 (2003) 245.
32. A.V. Makarycheva-Mikhailova, N.A. Bokach, V.Yu. Kukushkin*, P.F. Kelly*, L.M. Gilby, M.L. Kuznetsov, K.E. Holmes, M. Haukka, J. Parr, J.M. Stonehouse, M.R.J. Elsegood, A.J.L. Pombeiro*. Platinum(IV)-Mediated Nitrile-Sulfimide Coupling: A Route to Heterodiazadienes. Inorg. Chem., 42 (2003) 301.
33. A.I.F. Venancio, M.L. Kuznetsov, M.F.C. Guedes da Silva, L.M.D.R.S. Martins, J.J.R. Frausto da Silva, A.J.L. Pombeiro*. Metal—hydride bond activation and metal—metal interaction in dinuclear iron complexes with linking dinitriles: a synthetic, electrochemical and theoretical study. Inorg. Chem., 41 (2002) 6456.
34. K.V. Luzyanin, V.Yu. Kukushkin*, M.L. Kuznetsov, D.A. Garnovskii, M. Haukka, A.J.L. Pombeiro*. Novel Reactivity Mode of Hydroxamic Acids: a Metalla-Pinner Reaction. Inorg. Chem., 41 (2002) 2981.
35. K.V. Luzyanin, M. Haukka, N.A. Bokach, M.L. Kuznetsov, V.Yu. Kukushkin*, A.J.L. Pombeiro*. Platinum(IV)-mediated Hydrolysis of Nitriles Giving Metal-bound Iminols. J. Chem. Soc., Dalton Trans., (2002) 1882.
36. N.A. Bokach, V.Yu. Kukushkin*, M.L. Kuznetsov, D.A. Garnovskii, G. Natile, A.J.L. Pombeiro*. Direct Addition of Alcohols to Organonitriles Activated by Ligation to a Platinum(IV) Center. Inorg. Chem., 41 (2002) 2041.
37. L. Zhang, M.F.C. Guedes da Silva, M.L. Kuznetsov, M.P. Gamasa, J. Gimeno*, J.J.R. Frausto da Silva, A.J.L. Pombeiro*. Synthesis, Electrochemical and Theoretical Studies of Fisher-type Alkenyl-Carbyne Tungsten Complexes [(dppe)(CO)2(RNC)W{CCH=CCH2CH2(CH2)nCH2}][BF4] (R = alkyl, aryl). Organometallics, 20 (2001) 2782.
38. M.L. Kuznetsov*, A.I. Dement’ev, V.V. Zhornik. Ab initio Study of Structure, Protonation and Complex Formation of Novel Pyrazolone-5 Derivatives. J. Molec. Struct. (THEOCHEM), 571 (2001) 45.
39. M.L. Kuznetsov*, A.I. Dement’ev. Theoretical study of the reaction mechanism of nucleophilic addition of oximes to the complex trans-[PtCl4(NCCH3)2]. Russ. J. Coord. Chem., 28 (2002) 191.
40. M.L. Kuznetsov*, A.I. Dement’ev, O.S. Shestakova, V.Yu. Kukushkin. Theoretical study of activation of coordinated acetonitrile and reactivity of platinum organonitrile complexes. Russ. J. Inorg. Chem., 46 (2001) 1528.
41. K.A. Lysenko*, M.L. Kuznetsov, Yu.N. Medvedev, B.E. Zaitsev. Molecular structure of diantipyrilphenilmethane and its complex with neodimium nitrate. Crystallography Reports, 47 (2002) 262.
42. M.L. Kuznetsov, A.J.L. Pombeiro*, A. I. Dement’ev. Ab initio study of the protic conversion of an allene into an eta2-vinyl complex of Re, and on their structure, bonding and redox behaviour. J. Chem. Soc., Dalton Trans., (2000) 4413.
43. M.L. Kuznetsov, N.A. Bokach, V.Yu. Kukushkin*, T. Pakkanen, G. Wagner, A.J.L. Pombeiro*. Metal-assisted coupling of oximes and nitriles: a synthetic, structural and theoretical study. J. Chem. Soc., Dalton Trans., (2000) 4683.
44. V.Yu. Kukushkin*, T.B. Pakhomova, N.A. Bokach, G. Wagner, M.L. Kuznetsov, M. Galanski, A.J.L. Pombeiro*. Iminoacylation.3. Formation of platinum(IV)-based metallaligands due to facile one-end addition of vic-dioximes to coordinated organonitriles. Inorg. Chem., 39 (2000) 216.
45. M.L. Kuznetsov*, V.K. Bel’skii, A.I. Dement’ev, B.E. Zaitsev, B.V. Lokshin, V.V. Zhornik. X-Ray diffraction analysis and spectral studies of new derivatives of pyrazol-5-one. Russ. Chem. Bull., 48 (1999) 1274.
46. M.L.Kuznetsov*, A.I. Dementiev, S.V. Krasnoshchoikov. Theoretical study of some pyrazole derivatives and rare earth metal complexes. J. Molec. Struct. (THEOCHEM), 453 (1998) 17.
47. Yu.N. Medvedev*, M.L.Kuznetsov, K.A. Lysenko, M.Yu. Antypin, B.V. Lokshin. Neodimium 1,4-dioxanenitrato complex: structure and spectral properties. Russ. J. Inorg. Chem., 43 (1998) 368.
48. A.I. Dementiev*, M.L.Kuznetsov, Yu.M. Kiselev. On Extremal Oxidation States of Heavy 5d-Elements. Russ. J. Inorg. Chem., 42 (1997) 1052.
49. M.L.Kuznetsov*, Yu.N. Medvedev. Stability Constants for the Complexes of Anhydrous Lanthanide Nitrates with Diantipyrylphenylpropylmethane. Russ. J. Coord. Chem., 23 (1997) 205.
50. M.L.Kuznetsov*, Yu.N. Medvedev, V.K. Belskiy, A.I. Dementiev, B.E. Zaitsev. Structure and Spectral Properties of Complexes Ln(NO3)3 with Amidopyrine. Russ. J. Inorg. Chem., 42 (1997) 1000.
51. M.L.Kuznetsov*, Yu.N. Medvedev, F.M. Spiridonov. Complexes of Anhydrous Lanthanide Nitrates with Diantipyrylmethane. Russ. J. Coord. Chem., 22 (1996) 212.
52. M.L.Kuznetsov*, Yu.N. Medvedev, B.E. Zaitsev, V.M. Ivanov. Composition and Formation Constants of Complexes of Anhydrous Lanthanide Nitrates with Diantipyrylphenylmethane in Nonaqueous Solutions. Russ. J. Inorg. Chem., 40 (1995) 1257.
53. M.L.Kuznetsov*, Yu.N. Medvedev, B.E. Zaitsev, B.V. Lokshin, F.M. Spiridonov. Complexes of Anhydrous Lanthanide Nitrates with Diantipyrylphenylmethane and Diantipyrylphenylpropylmethane. Russ. J. Inorg. Chem., 40 (1995) 247.
54. Yu.N. Medvedev*, M.L.Kuznetsov, B.E. Zaitsev, B.V. Lokshin, F.M. Spiridonov. Complex Formation of Anhydrous Lanthanide Nitrates with Amidopyrine. Russ. J. Inorg. Chem., 39 (1994) 1438.
55. Yu.N. Medvedev*, M.L.Kuznetsov, B.V. Lokshin. Complex of lanthanide nitrates with 1,4 dioxane. Russ. J. Inorg. Chem., 39 (1994) 1585.
56. Yu.N. Medvedev*, B.E. Zaitsev, M.L.Kuznetsov, B.V. Lokshin, F.M. Spiridonov. Comlex Formation of Anhydrous Lanthanide Nitrates with Antipyrine in Dioxane Solutions. Russ. J. Inorg. Chem., 38 (1993) 1713.