Clementina Mesaros in Chemforum

Clementina Mesaros, from the Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, will be the next Chemforum speaker, which will be held on the 4^th of October, Wednesday, at 15:00 in QA02.2 in the Chemistry Tower.

Clementina Mesaros is a Research Assistant Professor of Pharmacology in the Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia. She received her Ph.D. in organic chemistry from Case Western Reserve University in 2005, then joined the Blair laboratory at the University of Pennsylvania were she quickly mastered the use of liquid chromatography-mass spectrometry (LC-MS) and developed a chiral method to monitor the oxidative modifications that arise from the cytochrome P-450 (CYP)-mediated metabolism of arachidonic acid. After her post-doctoral fellowship, she was appointed as the Technical Director of the Translational Biomarkers Core from the Center of Excellence in Environmental Toxicology (CEET) where she developed assays for metabolites involved in cellular oxidative stress and flux analysis of metabolites within intermediate metabolic pathways using stable-isotope dilution LC-MS.  One of Mesaros’ group current research is investigating how lipid metabolism is disrupted as a consequence of mitochondrial dysfunction in Friedreich’s ataxia (FRDA), a rare neurodegenerative disease.