| Publication Type |
Journal Article |
| Title |
Efficient regioselective synthesis of 4-and 5-substituted isoxazoles under thermal and microwave conditions |
| Authors |
Jamal Lasri Suman Mukhopadhyay Adilia Charmier |
| Groups |
|
| Journal |
JOURNAL OF HETEROCYCLIC CHEMISTRY |
| Year |
2008 |
| Month |
September |
| Volume |
45 |
| Number |
5 |
| Pages |
1385-1389 |
| Abstract |
The [2+3] cycloaddition reaction between nitrile oxides 2 and the captodative olefins 1 or the methyl crotonate derivatives 4 is regioselective and leads to the formation of the 5-substituted amino-isoxazole 3 or the 4-substituted methoxycarbonyl-isoxazole 5 derivatives, respectively. All these reactions are greatly accelerated by microwave irradiation without changing their regioselectivity with respect to the thermal conditions. |
| DOI |
http://dx.doi.org/ |
| ISBN |
|
| Publisher |
WILEY-BLACKWELL |
| Book Title |
|
| ISSN |
0022-152X |
| EISSN |
1943-5193 |
| Conference Name |
|
| Bibtex ID |
ISI:000259245800021 |
| Observations |
|
