Publication Type |
Journal Article |
Title |
Isomeric Furanosesquiterpenes from the Portuguese Marine Sponge Fasciospongia sp. |
Authors |
Helena Gaspar Susana Santos Marianna Carbone Ana Sofia Rodrigues Maria J. Uriz Sonia Murta Savluchinske Feio Dominique Melck Madalena Humanes Margherita Gavagnin |
Groups |
HC |
Journal |
JOURNAL OF NATURAL PRODUCTS |
Year |
2008 |
Month |
December |
Volume |
71 |
Number |
12 |
Pages |
2049-2052 |
Abstract |
This paper reports the chemical study of a sample of Fasciospongia sp. collected along the Atlantic Portuguese coast. Three new isomeric furanosesquiterpenes, isomicrocionin-3 (1), (-)-microcionin-1 (2), and (-)-isomicrocionin-1 (3), were isolated along with the known (-)-ent-pallescensin A (4) and (-)-pallescensin-1 (5) from the ethyl acetatesoluble portion of the methanolic extract. The structures of the new compounds were elucidated by extensive spectroscopic studies. (-)-Microcionin-1 (2) tested positive against several Gram-negative bacteria. |
DOI |
http://dx.doi.org/10.1021/np800346c |
ISBN |
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Publisher |
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Book Title |
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ISSN |
0163-3864 |
EISSN |
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Conference Name |
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Bibtex ID |
ISI:000262002800016 |
Observations |
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