Nuno Manuel Ribeiro Martins Xavier

Orcid number 0000-0001-8739-8768 Researcher id

11 Carbohydrate Chemistry


nmxavier@fc.ul.pt Phone: Fax: www: http://webpages.fc.ul.pt/~nmxavier/

-PhD in Organic Chemistry (2011, Universidade de Lisboa, Institut National des Sciences Appliqués de Lyon); -Postdoctoral Researcher at Universität für Bodenkultur, Vienna (2011/2012) and afterwards at Universidade de Lisboa (2012/2013). -Assistant Researcher (Investigador FCT) at Faculdade de Ciências, Universidade de Lisboa (2014/2018). -Research interests are encompassed within organic synthesis/medicinal chemistry focusing carbohydrate derivatives, nucleosides and nucleotides.

Selected Papers

Synthesis and biological evaluation of structurally varied 5´-/6´-isonucleosides and theobromine-containing N-isonucleosidyl derivatives
PHARMACEUTICALS, 12, 103 2019
Nuno Manuel Xavier , Eduardo C. de Sousa , Margarida P. Pereira , Anne Loesche , Immo Serbian , Rene Csuk , M. Conceição Oliveira

Novel dodecyl-containing azido and glucuronamide-based nucleosides exhibiting anticancer potential
PURE AND APPLIED CHEMISTRY, 91, 1085–1105 2019
Nuno Manuel Xavier , Rita Goncalves-Pereira , Radek Jorda , Denisa Hendrychová , M. Conceição Oliveira

Furanosyl Nucleoside Analogues Embodying Triazole or Theobromine Units as Potential Lead Molecules for Alzheimer s Disease
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, , 2667-2681 6 2018
Rita Goncalves-Pereira , Margarida P. Pereira , Sofia G. Serra , Anne Loesche , Rene Csuk , Samuel Silvestre , Paulo J. Costa , M. Conceição Oliveira , Nuno Manuel Xavier

Synthesis of glucopyranos-6 -yl purine and pyrimidine isonucleosides as potential cholinesterase inhibitors. Access to pyrimidine-linked pseudodisaccharides through Mitsunobu reaction
PURE AND APPLIED CHEMISTRY, 88, 363-379 4 2016
Daniela Batista , Stefan Schwarz , Anne Loesche , Rene Csuk , Paulo J. Costa , M. Conceição Oliveira , Nuno Manuel Xavier

Exploitation of new structurally diverse D-glucuronamide-containing N-glycosyl compounds: synthesis and anticancer potential
ORGANIC & BIOMOLECULAR CHEMISTRY, 15, 4667-4680 6 2017
Nuno Manuel Xavier , Alexandre Porcheron , Daniela Batista , Radek Jorda , Eva Reznickova , Vladimir Krystof , M. Conceição Oliveira