| Publication Type |
Journal Article |
| Title |
Use of Organomolybdenum Compounds for Promoted Hydrolysis of Phosphoester Bonds in Aqueous Media |
| Authors |
Ana C. Gomes Carla A. Gamelas Jose A. Fernandes Filipe A. Almeida Paz Patrique Nunes Martyn Pillinger Isabel S. Goncalves Carlos C. Romao M Abrantes |
| Groups |
|
| Journal |
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY |
| Year |
2014 |
| Month |
August |
| Volume |
|
| Number |
23 |
| Pages |
3681-3689 |
| Abstract |
The dissolution of the indenyl (Ind) complex [\(eta(5)-Ind)Mo(CO)(2)(mu-Cl)\(2)] (1) in N,N -dimethylformamide (DMF) gives the ring-slipped complex [(eta(3)-Ind)Mo(CO)(2)Cl(DMF)(2)] (2). The aerial oxidation of 2 leads to the formation of the dinuclear oxomolybdenum(V) chloride [Mo2O2(DMF)(4)(mu-O)(2)Cl-2] (3). The structures of 2 and 3 DMF have been determined by single-crystal X-ray diffraction. Compounds 1 and 3 were examined as promoters of phosphoester bond hydrolysis in para-nitrophenylphosphate (pNPP), which was used as a model substrate. The reactions were performed in aqueous solution at 55 degrees C and followed by H-1 NMR spectroscopy. For assays performed with 30-100 mol-\% of 1 or 3 relative to pNPP, both compounds promote the production of para-nitrophenol (pNPh) from pNPP. Compound 3 is especially active in promoting the hydrolytic cleavage of the phosphoester bond (t(1/2) < 80 min). |
| DOI |
http://dx.doi.org/10.1002/ejic.201402071 |
| ISBN |
|
| Publisher |
WILEY-V C H VERLAG GMBH |
| Book Title |
|
| ISSN |
1434-1948 |
| EISSN |
1099-0682 |
| Conference Name |
|
| Bibtex ID |
ISI:000340564700008 |
| Observations |
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