Publication Type |
Journal Article |
Title |
Catalyst-dependent selectivity in sulfonium ylide cycloisomerization reactions |
Authors |
Rik Oost James D. Neuhaus Antonio Misale Ricardo Meyrelles Luis F. Veiros Nuno Maulide |
Groups |
IOARC |
Journal |
CHEMICAL SCIENCE |
Year |
2018 |
Month |
September |
Volume |
9 |
Number |
35 |
Pages |
7091-7095 |
Abstract |
Divergent catalysis is an emerging field whereby access to structurally diverse compounds from a common precursor is achieved through controlled reaction pathways. Herein we present an unusual example of -acid catalyst dependent selectivity in the cycloisomerization of alkene-tethered sulfonium ylides. Computational mechanistic studies revealed how the ability of palladium to cycle through oxidation states largely controls the selectivity. |
DOI |
http://dx.doi.org/10.1039/c8sc02815j |
ISBN |
|
Publisher |
|
Book Title |
|
ISSN |
2041-6520 |
EISSN |
2041-6539 |
Conference Name |
|
Bibtex ID |
ISI:000445777400007 |
Observations |
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